is a vaccine approved June 8, 2006 by the U.S. Food and Drug Administration (FDA) for use in the prevention of certain types of human papillomavirus (HPV),[3] specifically HPV types 6, 11, 16 and 18.[4][5] HPV types 16 and 18 cause an estimated 70% of cervical cancers,[6][7] and are responsible for most HPV-induced anal,[8] vulvar, vaginal,[9] and penile cancer cases. HPV types 6 and 11 cause an estimated 90% of genital warts cases.