The Blood Syndicate differed from other supergroups in that they were (in Velez's words) "not a team - they're a gang". In fact, they were the surviving remnants of multiple street gangs (thus the name, a combination of "Paris Island Bloods" and "Force Syndicate"), who had gained superpowers in the so-called Big Bang, and decided to use them for a greater purpose. However, their constant in-fighting, the unsustainability of their methods, and their lack of a central vision (particularly after the death of their first leader) led to the Syndicate's eventual disintegration.